As the mast cells destroy the allergens, a chemical called histamine is released into the bloodstream. A large amount of histamine swells body tissues (inflammation), causes itching, enlarges blood vessels, increases secretions, and causes bronchospasm (tightening of muscles that surround the airways).Click to see full answer. Simply so, can allergies cause chronic inflammation? Chronic allergic inflammation When allergen exposure is continuous or repetitive, inflammation persists, and many innate and adaptive immune cells derived from the blood can be found in the tissues at sites of allergen challenge. what is the main cause of inflammation in the body? Inflammation is the body’s response to injury. Chronic inflammation has been linked to certain diseases such as heart disease or stroke, and may also lead to autoimmune disorders, such as rheumatoid arthritis and lupus. But a healthy diet and lifestyle can help keep inflammation under control. Similarly, you may ask, how do you reduce inflammation from allergies? The following treatments are commonly used to reduce the symptoms of an allergic reaction: Antihistamines. Nasal decongestants. Anti-inflammatory medication. Avoid the allergen. Use a saline sinus rinse. Treating environmental allergies. Treating allergies on the skin. Treating severe allergies. What are the 5 classic signs of inflammation?The five classical signs of inflammation are heat, pain, redness, swelling, and loss of function (Latin calor, dolor, rubor, tumor, and functio laesa).