Many allergy drugs may be fine to keep taking during pregnancy, but have the discussion so you can have peace of mind. Oral antihistamines, like cetirizine (Zyrtec), chlorpheniramine (Chlor-Trimeton), diphenhydramine (Benadryl), fexofenadine (Allegra), and loratadine (Claritin) seem to be safe.Click to see full answer. Keeping this in consideration, is cetirizine safe in second trimester?Second-generation antihistamines, such as cetirizine (CTZ) and loratadine, are considered safe in pregnancy and are not associated with an increased risk for major congenital malformations (Li et al. 2013. Assessment of antihistamine use in early pregnancy and birth defects.Subsequently, question is, does cetirizine cross the placenta? The low molecular weight of cetirizine makes it highly likely to cross the placental barrier during pregnancy. Cetirizine is an active metabolite of hydoxyzine (a first generation antihistamine), which is generally considered safe for use during pregnancy. Cetirizine would not be anticipated to cause harm either. Keeping this in consideration, which antihistamine is best in pregnancy? Chlorphenamine is also considered one of the safer antihistamines to take during pregnancy, but because it can cause drowsiness, loratadine and cetirizine are usually the preferred options. For information about taking specific medicines in pregnancy, see the bumps (best use of medicines in pregnancy) website.What are the side effects of cetirizine? That said, Cetirizine can cause adverse effects, such as: drowsiness. excessive tiredness. dry mouth. stomach pain. diarrhea. vomiting.
