Preseptal cellulitis, also known as periorbital cellulitis, is an infection in the tissues around the eye. It can be caused by minor trauma to the eyelid, such as an insect bite, or the spread of another infection, such as a sinus infection.Click to see full answer. Also question is, what causes periorbital cellulitis in adults?Periorbital cellulitis is an infection of your eyelid or the skin around your eyes. It happens when bacteria attack the soft tissue around your eye, including your eyelid. These germs can get into your skin through a cut or scratch, or they can get to the area through an infection in your sinuses.Beside above, is periorbital cellulitis dangerous? You may have heard of cellulitis, a dangerous skin infection, that, if not treated properly, can be fatal. Well, it gets worse: You can actually contract periorbital (also called preseptal) cellulitis in your eye. Just so, what is the treatment for periorbital cellulitis? The current recommendation is Clindamycin or TMP-SMX plus Amoxicillin-clavulanic acid or Cefpodoxime or Cefdinir. If the patient is unimmunized by H. influenzae, antibiotic coverage with a beta-lactam is recommended. The antibiotic course is usually for five to seven days or longer if the cellulitis persists.What is periorbital cellulitis?Preseptal cellulitis (periorbital cellulitis) is infection of the eyelid and surrounding skin anterior to the orbital septum. Orbital cellulitis usually begins deep to the orbital septum. Both are more common among children; preseptal cellulitis is far more common than orbital cellulitis.