Yes, Vivitrol blocks the effects of all opioids in the brain. Vivitrol is a blocker; if someone took suboxone on Vivitrol, there would be no euphoric effect in the user. This does not mean that while on the monthly shot for opioid addiction that you cannot overdose by using opioids.Click to see full answer. Similarly, you may ask, how long after Suboxone can you take vivitrol?After the initial titration period for opioid withdrawal (of up to 8 days), patients will receive the Vivitrol injection. Then, we will follow patients for retention out to 4 weeks.Additionally, can you reverse vivitrol? Once administered, the opioid-blocking effects of VIVITROL are expected to last approximately 28 days. In an emergency situation, reversal of the VIVITROL blockade may be required for pain management. Please review the safety information for When Reversal of VIVITROL Blockade is Required for Pain Management. In this manner, can naltrexone be taken with Suboxone? Using naltrexone together with buprenorphine is not recommended. Naltrexone can block the effects of buprenorphine and make the medication less effective in treating your condition. If you have been receiving buprenorphine for a while (for example, a week or longer), naltrexone can also precipitate withdrawal symptoms.Does vivitrol have buprenorphine?While buprenorphine partially stimulates opioid receptors, naltrexone, the active ingredient in Vivitrol, blocks those receptors. Vivitrol is a once-a-month, extended-release injection that can treat problems with alcohol as well as heroin or pain pills.