But for cooking and flavoring uses, yes, you can freeze lettuce. The reason you won’t be able to use the frozen lettuce to make salads is because the freezing process causes ice crystals to form in plant cells. But lettuce has such a high water content that freezing produces more of a slimy mess.Click to see full answer. Keeping this in view, can you get sick from frozen lettuce?It won’t hurt you, but salads don’t like to be frozen. They respond by turning slimy and mushy—particularly if they are composed of various lettuces and vegetables.Additionally, how do you thaw frozen lettuce? Just remove the lettuce from its frozen packaging and place the leaves at room temperature flat on a few paper towels to defrost. You could also lay out the greens on a dish towel to defrost. This will help absorb moisture as the frozen lettuce slowly thaws out. In this regard, is frozen lettuce poisonous? But, other vegetables, like lettuce and cucumbers, have a lot of water in them and more delicate cell walls. The ice crystals damage these vegetables so badly that they really can’t be frozen without turning into mush. Slow freezing creates larger ice crystals than fast freezing and causes more damage.Why does lettuce freeze in the refrigerator?Lettuces, like other leafy greens, are more likely to freeze than other produce because they hold a lot of water in their leaves, according to the New York Times.